You are not logged in.


Unread posts

Dear visitor, welcome to FertilityZone . If this is your first visit here, please read the Help. It explains in detail how this page works. To use all features of this page, you should consider registering. Please use the registration form, to register here or read more information about the registration process. If you are already registered, please login here.

  • "THE FZ TEAM" started this thread

Posts: 2,129

Reg: Oct 19th 2006

What's Up?
Tech support is currently limited

Thanks: 29 / 12

  • Send private message

1

Wednesday, April 23rd 2008, 9:46am

HCG LEVELS IN PREGNANCY

What Do the Numbers Mean?
The problem is, once a pregnancy is confirmed, you need to know if it progressing along normally. Keeping track of HCG numbers is one way of measuring fetal viability. HCG is measured in milli-international units per millimeter (mIU/ml). HCG is first detectable in the blood as early as seven or eight days after ovulation by very sensitive HCG assays. Blood pregnancy tests will be positive (> 2 mIU/ml) by 10 or 11 days after HCG injection or LH surge, and levels vary with gestational age during pregnancy.

There is a large variation in a "normal" HCG level for any given time in pregnancy. Caution must be used in making too much of HCG "numbers." Ultrasound findings after five or six weeks of pregnancy are much more predictive of pregnancy outcome than are HCG levels. You won't expect to see a gestational sac or the fetus until the HCG level reaches approx 2000 mIU/ml.

However, a single HCG level cannot indicate a normal pregnancy. In a normal pregnancy there is a regular increase of the HCG, so you need to see more than one value before you can better understand what's going on. Additionally, a single value cannot always tell you how far along the pregnancy is, because of the wide range of blood HCG levels in pregnancy. To illustrate the limitations of looking at a single measurement, here is a sample reference list for HCG levels in singleton pregnancies, based on days past ovulation (DPO):

* At 14 DPO, the average HCG level is 48 mIU/ml, with a typical range of 17-119 mIU/ml.
* At 15 DPO, the average HCG level is 59 mIU/ml, with a typical range of 17-147 mIU/ml.
* At 16 DPO, the average HCG level is 95 mIU/ml, with a typical range of 33-223 mIU/ml.
* At 17 DPO, the average HCG level is 132 mIU/ml, with a typical range of 17-429 mIU/ml.
* At 18 DPO, the average HCG level is 292 mIU/ml, with a typical range of 70-758 mIU/ml.
* At 19 DPO, the average HCG level is 303 mIU/ml, with a typical range of 111-514 mIU/ml.
* At 20 DPO, the average HCG level is 522 mIU/ml, with a typical range of 135-1690 mIU/ml.
* At 21 DPO, the average HCG level is 1061 mIU/ml, with a typical range of 324-4130 mIU/ml.
* At 22 DPO, the average HCG level is 1287 mIU/ml, with a typical range of 185-3279 mIU/ml.
* At 23 DPO, the average HCG level is 2034 mIU/ml, with a typical range of 506-4660 mIU/ml.
* At 24 DPO, the average HCG level is 2637 mIU/ml, with a typical range of 540-10,000 mIU/ml.

Accordingly, the key to interpreting the true value of HCG measurements is to look at their progression. In general, the HCG level will double every two to three days in early pregnancy. Approximately 85 percent of normal pregnancies will have the HCG level double every 72 hours. However, as you get further along in your pregnancy and the HCG levels get higher, the expected doubling time increases.

* For HCG levels <1200 mIU/ml, the expected doubling time is 48-72 hours.
* For HCG levels 1200 to 6000 mIU/ml, the expected doubling time is 72-96 hours.
* For HCG levels >6000 mIU/ml, the expected doubling time is >96 hours.

HCG levels peak at about eight to 10 weeks of pregnancy and then decline, remaining at lower levels for the rest of the pregnancy. Here is a sample listing of expected HCG levels based on time after conception:

* 0-1 week: 0-50 mIU/ml
* 1-2 weeks: 40-300 mIU/ml
* 3-4 weeks: 500-6,000 mIU/ml
* 1-2 months: 5,000-200,000 mIU/ml
* 2-3 months: 10,000-100,000 mIU/ml
* 2nd trimester: 3,000-50,000 mIU/ml
* 3rd trimester: 1,000-50,000 mIU/ml
* Non-pregnant females: <5.0 mIU/ml
* Postmenopausal females: <9.5 mIU/ml

This is only a guide so shouldn't be taken as the levels you have to have. Always check with your Consultant when they give you any readings, ask if they consider that within the correct limits.

Please don't panic if you are given a reading that you think falls outside these levels.... again, go back to your Cons or clinic and ask for re-assurance.


LINK




FERTILITYZONE



MEDHURST – PROUD HOSTS OF FERTILITYZONE